Innovative Solutions for Drug Discovery
Hit Identification
Hit Identification
Hit ID begins with a clear, focused screening strategy that is appropriate for the target, integrating insights from biophysics and enzymology to enhance the effectiveness of drug discovery consulting. Our approach includes a robust screening strategy and development process, CRO management, meticulous data analysis, and thorough druggability assessment, all designed to optimize lead optimization strategies.
Hit Validation
Hit Identification
We help clients prioritize screening hits to ensure that chemistry efforts are concentrated on those with the highest likelihood of becoming leads, which is essential in drug discovery consulting. Our expertise spans biophysics and enzymology, focusing on critical areas such as biophysical characterization, solubility assessment, target-ligand engagement, and mechanism of action, all of which are vital for implementing effective lead optimization strategies.
Lead Optimization
Lead Optimization
Once leads have been identified, we utilize lead optimization strategies through advanced structural and biophysical methods. Our expertise in biophysics and enzymology enhances our drug discovery consulting, employing techniques such as Structure-Based Drug Design (X-ray, Cryo-EM) and Biophysical Analysis (SPR, ITC, TSA, BLI, Mass Photometry).
SPR Microscopy
In addition to consulting services, we are an independent representative for Biosensing Instruments (Flagstaff, AZ, USA), specializing in SPR microscopy.
